• Israel carried out a limited military strike against Iran and is assessing its effectiveness and the damage it caused, a source familiar with the situation told NBC News.

• Iranian state media reports that air defense systems were engaged in several provinces and that nuclear sites in Isfahan, in central Iran, are safe. Meanwhile, the state media appeared to downplay the impact of a possible Israeli strike in the country.

• Secretary of State Antony Blinken said the United States had "not been involved in any offensive operations" when asked about the Israeli strike on Iran. Separately, a source familiar with the matter told NBC News that Israeli officials notified the U.S. that a response was coming.

• Flights in Iran resumed with no restrictions today. A state run news agency reported earlier that flights were suspended in the cities of Tehran, Isfahan and Shiraz.

• Israel had vowed it would respond to Iran's retaliatory attack Saturday, when Iran fired more than 300 drones and missiles at Israel in its first direct military assault on the country. The strikes did not cause widespread damage or death.

Story Date: April 22, 2024